These will work for you but they will need to be notched out to make room for the hump that is in the front wheel well. They are not a custom fit for the RAM.
We do have 2 custom fit options for the 2018 RAM 2500 HD
With OEM flares - https://www.sharptruck.com/truck-hardware-gatorback-mud-flaps-gcr31f-bk
Without OEM flares - https://www.sharptruck.com/truck-hardware-gatorback-mud-flaps-gcr32f-bk
Craig, Gatorback flaps are covered by a limited lifetime warranty for things like tear offs. If you send a pic of the damaged flap to [email protected] we can send out a new rubber flap for no charge. Just transfer the plate from the old flap to the new one.
They are a universal mud flap and come with 8 self tapping screws. Here is the custom fit set for the truck, https://www.sharptruck.com/truck-hardware-gcr407k-bk